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Effects of O-box guided taste steering in chemotherapy induced taste changes


Taste changes are a common side effect of chemotherapy. About half of people receiving chemotherapy experience taste changes during and after therapy. Taste changes can lead to loss of appetite, weight loss, food aversions and a reduced quality of life.
Today, there are no specific treatments for chemotherapy induced taste problems. Relieving such side effects is one of the goals of
primary food care and as such it will become an important part of cancer care and treatment. The aim of this research is to validate the use
‚Äčof the handy taste screening tool (called O-box), to determine the taste profile in a standard population and to explore the effects of O-box guided taste steering in chemotherapy induced taste changes.

Following research questions will be answered in the PhD project:

The aim of this PhD is to prove the effectiveness and the efficiency of taste steering through the O-box fighting against malnutrition and loss of quality of life for oncopatients with taste alterations during chemotherapy. Research questions:

  1. Mapping the taste profiles of a standard population through the O-box:
    • How does this standard profile looks like?
    • Can we distinguish clusters in the distribution?
    • What are the univariate characteristics of the distribution?
  2. Do oncopatients have an aberrant taste profile through the O-box?
  3. What is the effect of taste steering on oral intake and BMI of the oncological patient with taste alterations during treatment with chemotherapy?
  4. What is the effect of taste steering on Quality of Life of the oncological patient with taste alterations during treatment with chemotherapy and on the quality of life of the patients family and/or caregiver?
  5. How is taste steering experienced by the family or caregivers and by the oncopatient with taste alterations during treatment with chemotherapy?


PhD-student:
Marleen Corremans, RN, MSc.
University of Antwerp

Promotors:
Prof. Dr. Bart Geurden
University of Antwerp (Belgium)
Faculty of Medicine and Health Sciences
Center for Research and Innovation in Care (CRIC)

Prof.Dr.Dimitri Mortelmans
University of Antwerp (Belgium)
Faculty of Political and Social Sciences
Centre for Longitudinal and Life Course Studies (CELLO)
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In collaboration with